Factor V assay, clotting factor tests
A factor V test is a blood test that checks for a deficiency in a protein known as factor V. Factor V is a protein that helps your blood to clot. Having too little factor V causes a rare bleeding disorder. Your body has a number of protein "clotting factors." They are identified by Roman numerals.
Factor V deficiency is an inherited disorder. It is called an autosomal recessive gene disorder. This means both parents must have the defective gene and pass it on to their children for this to occur.
If you have certain symptoms, such as unexplained or extra bleeding or bruising, it may mean that your blood is not clotting the way it should. You might have a deficiency in one of the clotting factors. Your healthcare provider may do a blood test to check for the presence and function of the individual clotting factors to see if you have a deficiency in any of them.
Along with tests to check for factor V deficiency, your healthcare provider might check your blood for deficiencies in other clotting factors.
A result for a lab test may be affected by many things, including the method the laboratory uses to do the test. If your test results are different from the normal value, you may not have a problem. To learn what the results mean for you, talk with your healthcare provider.
In a test of your clotting factors, the results are usually given as a percentage. So if you get a result of 100%, it means your factor V is at 100% of its normal value. Levels between 25% and 60%mean a mild factor V deficiency. This usually causes no symptoms. Levels of 1% to 10% are severely low and can lead to major bleeding issues.
The test requires a blood sample, which is drawn through a needle from a vein in your arm.
Taking a blood sample with a needle carries risks that include bleeding, infection, bruising, or feeling dizzy. When the needle pricks your arm, you may feel a slight stinging sensation or pain. Afterward, the site may be slightly sore.
A deficiency of factor V is quite rare (about 1 in 1 million) and can be a genetic disorder passed on from parents to their children. But some clotting factors, including factor V, can decrease because of certain illnesses, such as liver disease, cancers, autoimmune diseases, and a disease called disseminated intravascular coagulation. It can also occur after exposure to some toxins.
You don't need to prepare for this test.