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ABARELIX (Plenaxis™) was used to treat advanced prostate cancer when other treatments could not be used or were refused. Abarelix was available only from health care providers who participated in a special prescribing program. This drug is no longer available in the US. If you are currently taking abarelix, contact your prescriber for instructions. Your prescriber will provide you with information about which available drug treatment may be best for you.
NOTE: This drug is discontinued in the United States.
They need to know if you have any of these conditions:
heart problems or heart disease (such as prolonged QT syndrome or irregular heart beat)
an unusual reaction to Abarelix, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Abarelix is for injection into a muscle. Abarelix is only given to you by a health care professional.
It is important not to miss a dose. Call your prescriber or health care professional if you are unable to keep an appointment.
certain antibiotics (such as clarithromycin, erythromycin, gatifloxacin, gemifloxacin, grepafloxacin, levofloxacin, moxifloxacin, sparfloxacin, troleandomycin)
certain medicines to control the heart rhythm (such as amiodarone, disopyramide, dofetilide, flecainide, ibutilide, quinidine, procainamide, propafenone, sotalol)
certain medicines for depression or mental problems (such as amoxapine, haloperidol, maprotiline, risperidone, sertindole, tricyclic antidepressants, ziprasidone)
herbal or dietary supplements, like DHEA
female hormones, like estrogen
male hormones, like testosterone
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
You will wait in your doctor's office for 30 minutes after getting each injection of abarelix. Your doctor will do blood tests every 2 months to check the amount of testosterone in your blood. Your doctor may also do blood tests to check your liver function. Visit your prescriber or health care professional for regular checks on your progress.
Your health care professional will review a Medication Guide and a Patient-Physician Agreement with you prior to prescribing abarelix. You need to read and understand these materials. Tell your provider if you have any questions. If you are unable or unwilling to understand and comply with the Agreement and Medication Guide, you should not take abarelix. Read the Medication Guide before you first receive abarelix.
Side effects that you should report to your prescriber or health care professional as soon as possible:
fever, sore throat, or any symptoms of an infection
rapid heart beat or racing heart
rash, hives, itching, or redness of your skin
severe or persistent stomach pain
swelling of your face, eyelids, tongue, throat, feet or legs
yellowing of your skin or eyes
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
breast swelling or tenderness
decreased sexual desire or ability (impotence)
diarrhea or constipation
hot flashes (sudden feelings of warmth or sweating)
insomnia or sleep problems
loss of appetite
muscle and joint, or bone pains
redness or irritation at the injection site
This does not apply. This medicine is given by a health care professional in a clinic or office setting. You will not need to take this medicine at home.