Your healthcare provider may suggest an endometrial biopsy if you have:
Biopsy results may show cell changes linked to hormone levels, or abnormal tissues, such as fibroids or polyps. These can lead to abnormal bleeding. Your provider can also use endometrial biopsy to check for uterine infections, such as endometritis.
Your provider may also use an endometrial biopsy to check the effects of hormone therapy or to find abnormal cells or cancer. Endometrial cancer is the most common cancer of the female reproductive organs. Endometrial biopsy is no longer advised as a routine part of testing and treatment of infertility (not able to get pregnant).
Your healthcare provider may have other reasons to do an endometrial biopsy.
Some possible complications may include:
If you are allergic to or sensitive to medicines, iodine, or latex tell your healthcare provider.
If you are pregnant or think you could be, tell your healthcare provider. Endometrial biopsy during pregnancy may lead to miscarriage.
There may be other risks based on your condition. Be sure to talk about any concerns with your healthcare provider before the procedure.
Certain things may interfere with an endometrial biopsy including:
An endometrial biopsy may be done in a healthcare provider's office, on an outpatient basis, or as part of your stay in a hospital. Procedures may vary based on your condition and your healthcare provider’s practices.
Generally, an endometrial biopsy follows this process:
After the procedure, you may rest for a few minutes before going home. If you had any type of sedative, you will need someone to drive you home.
You may want to wear a sanitary pad for bleeding. It is normal to have some mild cramping and spotting or vaginal bleeding for a few days after the procedure. Take a pain reliever as advised by your healthcare provider. Aspirin or certain other pain medicines may increase the chance of bleeding. Be sure to take only recommended medicines.
Don’t douche, use tampons, or have sex for 2 to 3 days after an endometrial biopsy, or for a time recommended by your healthcare provider.
You may also have other limits on your activity, including no strenuous activity or heavy lifting.
You may go back to your normal diet unless your healthcare provider tells you otherwise.
Your healthcare provider will tell you when to return for further treatment or care.
Tell your healthcare provider if you have any of the following:
Your healthcare provider may give you other instructions after the procedure, based on your situation.
Before you agree to the test or the procedure make sure you know: