Emergency/Trauma care is practiced with a high level of expertise throughout the Detroit Medical Center, which offers Level I Trauma Centers at Children's Hospital of Michigan and Detroit Receiving Hospital (Southeast Michigan's first American College of Surgeons verified, Level One Trauma Center) . Emergency care at Detroit Receiving and Children's Hospital of Michigan is strengthened by the Detroit Medical Center's ongoing partnership with Wayne State University's School of Medicine (where physicians pioneered emergency and trauma care in the 1970s). Detroit Receiving and Children's hospitals also operate specialized burn units.

Expert emergency care is also available through Huron Valley-Sinai, and Sinai-Grace hospitals, and urgent care is available at many locations throughout the metropolitan area.